Colin D Funk Selected Research

cysteinyl-leukotriene

1/2020	A Novel Strategy to Mitigate the Hyperinflammatory Response to COVID-19 by Targeting Leukotrienes.
3/2012	The cysteinyl leukotriene 2 receptor mediates retinal edema and pathological neovascularization in a murine model of oxygen-induced retinopathy.
10/2008	Endothelial cysteinyl leukotriene 2 receptor expression and myocardial ischemia/reperfusion injury.
3/2008	Endothelial cysteinyl leukotriene 2 receptor expression mediates myocardial ischemia-reperfusion injury.
8/2007	PKC-dependent regulation of the receptor locus dominates functional consequences of cysteinyl leukotriene type 1 receptor activation.

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Colin D Funk Research Topics

Disease

16	Inflammation (Inflammations) 11/2019 - 09/2002
15	Atherosclerosis 07/2009 - 07/2002
9	Cardiovascular Diseases (Cardiovascular Disease) 04/2015 - 09/2004
9	Asthma (Bronchial Asthma) 11/2014 - 12/2002
5	Reperfusion Injury 01/2023 - 03/2008
5	Thrombosis (Thrombus) 12/2015 - 04/2005
4	Hyperplasia 10/2018 - 07/2013
4	Myocardial Infarction 01/2012 - 09/2004
4	Aortic Aneurysm (Aneurysm, Aortic) 08/2007 - 09/2004
3	COVID-19 01/2021 - 01/2020
3	Abdominal Aortic Aneurysm 07/2012 - 08/2007
3	Hypertension (High Blood Pressure) 05/2012 - 03/2005
3	Myocardial Ischemia (Ischemic Heart Diseases) 12/2011 - 03/2008
3	Neoplasms (Cancer) 01/2011 - 05/2003
3	Hyperlipidemias (Hyperlipidemia) 12/2010 - 09/2004
3	Aneurysm (Aneurysms) 01/2010 - 09/2004
3	Stroke (Strokes) 05/2006 - 09/2004
2	Disease Progression 01/2020 - 07/2004
2	Neointima 10/2018 - 07/2013
2	Vascular System Injuries 10/2018 - 04/2006
2	Infarction (Infarctions) 01/2018 - 03/2008
2	Atherosclerotic Plaque (Atheroma) 01/2017 - 09/2002
2	Hyperargininemia 12/2015 - 01/2013
2	Pulmonary Hypertension 03/2015 - 01/2011
2	Respiratory Hypersensitivity 11/2014 - 05/2004
2	Insulin Resistance 12/2010 - 03/2010
1	Body Weight (Weight, Body) 01/2021
1	Severe Acute Respiratory Syndrome 01/2020
1	Cytokine Release Syndrome 01/2020
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2020
1	Obesity 11/2019
1	Inborn Urea Cycle Disorders 01/2017
1	Carotid Artery Thrombosis 12/2015
1	Coronary Artery Disease (Coronary Atherosclerosis) 12/2015
1	Inborn Genetic Diseases (Disease, Hereditary) 12/2015
1	Hypoxia (Hypoxemia) 03/2015
1	Vascular Remodeling 07/2013

Drug/Important Bio-Agent (IBA)

11	LeukotrienesIBA 01/2020 - 12/2002
11	ApolipoproteinsIBA 12/2010 - 09/2002
9	Arachidonate 5-Lipoxygenase (5 Lipoxygenase)IBA 05/2010 - 07/2002
8	Apolipoproteins E (ApoE)IBA 01/2017 - 10/2004
7	Arachidonate 15-Lipoxygenase (Arachidonate 15 Lipoxygenase)IBA 12/2010 - 09/2002
6	LipidsIBA 01/2020 - 09/2004
6	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2018 - 05/2003
5	ProstaglandinsIBA 01/2023 - 05/2006
5	cysteinyl-leukotrieneIBA 01/2020 - 08/2007
5	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 10/2018 - 09/2002
4	EnzymesIBA 12/2015 - 05/2003
4	Angiotensin IIIBA 01/2010 - 03/2005
3	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 01/2018 - 04/2005
3	Protein Isoforms (Isoforms)IBA 01/2018 - 01/2013
3	Urea (Carbamide)FDA LinkGeneric 01/2017 - 01/2013
3	CholatesIBA 08/2007 - 09/2004
3	LDL Receptors (LDL Receptor)IBA 09/2002 - 07/2002
2	Amino Acids FDA Link 01/2021 - 01/2013
2	VaccinesIBA 01/2021 - 01/2020
2	5S,12R,18R- trihydroxy- 6Z,8E,10E,14Z,16E- eicosapentaenoic acidIBA 10/2018 - 01/2018
2	CytokinesIBA 01/2018 - 09/2002
2	MonocrotalineIBA 03/2015 - 01/2011
2	cysteinyl leukotriene receptor 2IBA 02/2014 - 12/2011
2	Messenger RNA (mRNA)IBA 01/2013 - 09/2002
2	Proteins (Proteins, Gene)FDA Link 01/2013 - 09/2004
2	Alanine Transaminase (SGPT)IBA 12/2010 - 03/2010
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2010 - 03/2010
2	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 12/2010 - 03/2010
2	InterleukinsIBA 12/2010 - 03/2010
2	Arachidonic Acid (Vitamin F)IBA 07/2009 - 05/2003
2	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 06/2009 - 11/2007
2	Epoprostenol (Prostacyclin)FDA LinkGeneric 06/2009 - 11/2007
2	Lipoxygenase (Lipoxygenase-1)IBA 06/2006 - 07/2004
2	ChemokinesIBA 11/2005 - 09/2004
1	Peroxidase (Myeloperoxidase)IBA 01/2023
1	zileuton (Zyflo)FDA Link 01/2020
1	Delayed-Action PreparationsIBA 01/2020
1	Dexamethasone (Maxidex)FDA LinkGeneric 01/2020
1	Generic DrugsIBA 01/2020
1	Glycoproteins (Glycoprotein)IBA 01/2020
1	Angiotensin-Converting Enzyme 2IBA 01/2020
1	montelukast (Singulair)FDA Link 01/2020
1	remdesivirIBA 01/2020
1	MicroRNAs (MicroRNA)IBA 11/2019
1	Eicosapentaenoic AcidIBA 10/2018
1	Fatty Acids (Saturated Fatty Acids)IBA 10/2018
1	OrnithineIBA 12/2015
1	Arginine (L-Arginine)FDA Link 12/2015
1	Fish OilsIBA 12/2015
1	ferric chlorideIBA 12/2015
1	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 04/2015
1	Nonesterified Fatty Acids (NEFA)IBA 04/2015
1	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 04/2015
1	AllergensIBA 11/2014
1	OvalbuminIBA 11/2014
1	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 07/2013
1	Monomeric GTP-Binding ProteinsIBA 07/2013
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 07/2013
1	glycocyamineIBA 01/2013
1	AmmoniaIBA 01/2013

Therapy/Procedure

5	Therapeutics 01/2020 - 04/2005
1	Stents 10/2018
1	Percutaneous Coronary Intervention 10/2018